Schatten H. The Centrosome and its Functions and Dysfunctions 2023

Textbook in PDF format

The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research.
Cell and Molecular Biology of Centrosome Structure and Function
The Centrosome Cycle within the Cell Cycle
Centrosome as Center for Proteolytic Activity and Dysfunctions Associated with Pathogenesis of Human Disease
Centrosome Dysfunctions in Cancer
Virus Exploitation (Hijacking) of Centrosomes
Centrosomes in Reproduction
Transitions from Centrosomal to Non-centrosomal Microtubule Organization During Cellular Polarization
External and Environmental Effects on Centrosomes
Centrosomes and Centrosome Equivalents in Other Systems
Non-centrosomal Microtubule Organization in Plant Cells