Chaouki J. Scale-up Processes. Iterative Methods for...Industries 2021

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Common scale-up methods are conventional where the blind piloting is essential. This imposes huge investment and leads to failures mostly in solid processing. However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting.
Preface
1 Conventional scale-up method: challenges and opportunities
2 Iterative scale-up method: concept and basics
3 Process extrapolation by simulation
4 Transition from e-pilot to full commercial scale
5 Life-cycle assessment and technology scale-up
6 Case study I: n-Butane partial oxidation to maleic anhydride: VPP manufacture
7 Case study II: n-Butane partial oxidation to maleic anhydride: commercial design
8 Case study III: Methanol to olefins
9 Case study IV: Hydropotash from potassium feldspar Terminology
10 Case study V: Lactide production process development
11 Case study VI: CO2 sequestration in microalgae photobioreactors
12 Discussion and concluding remarks