Jha T. Modeling Inhibitors of Matrix Metalloproteinases 2024

Textbook in PDF format

Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more. This book covers various modern molecular modeling methodologies particularly related to MMP inhibitors. Included in the text are descriptions of ligand-based drug designing and structure-based drug designing modeling strategies for designing potential and target specific or selective MMPIs. This book will benefit those who are looking for an in-depth text on the design and discovery processes of novel and selective MMPIs.
Fundamentals of Molecular Modeling
Matrix Metalloproteinases and Their Inhibitors
Modeling of MMP Inhibitors
Conclusion and Future Perspective