Marsh D. Drug Product Development for the Back of the Eye 2011

Textbook in PDF format

This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms, Refillable and microneedle devices, Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery, Physical methods including iontophoresis for drug delivery, Rational selection of routes of administration and delivery systems, Noninvasive and continuous drug monitoring, Clinical endpoints and regulatory path to drug product development, Emerging and existing drugs and drug targets