Umer S. Computational Techniques for Biological Sequence Analysis 2025

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Umer S. Computational Techniques for Biological Sequence Analysis 2025

Textbook in PDF format This book provides an overview of basic and advanced computational techniques for analyzing and understanding protein, RNA, and DNA sequences. It covers effective computing techniques for DNA and protein classifications, evolutionary and sequence information analysis, evolutionary algorithms, and ensemble algorithms. Furthermore, the book reviews the role of machine learning techniques, artificial intelligence, ensemble learning, and sequence-based features in predicting post-translational modifications in proteins, DNA methylation, and mRNA methylation, along with their functional implications. The book also discusses the prediction of protein–protein and protein–DNA interactions, protein structure, and function using computational methods. It also presents techniques for quantitative analysis of protein–DNA interactions and protein methylation and their involvement in gene regulation. Additionally, the use of nature-inspired algorithms to gain insights into gene regulatory mechanisms and metabolic pathways in human diseases is explored. This book acts as a useful reference for bioinformaticians and computational biologists working in the fields of molecular biology, genomics, and bioinformatics