Bagatini M. Purinergic System 2022

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Characterized as a common signaling pathway between cells, the purinergic system is capable of modulating physiological and biochemical processes. Composed of signaling molecules, regulatory enzymes, and specific receptors, this organization can modulate several basal pathways of the organism. It is understood that purinergic signaling is present in all aspects of immunity and inflammation and studies show that extracellular ATP and its adenosine metabolite are the main mediators of response. These occur since most immune cells express P2 and P1 receptors, which are sensitive to the ATP and adenosine molecules, respectively. This book describes the purinergic system and its correlation with the health and disease process.
Purinergic System in Immune Response
Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases
Purinergic Signaling in Covid-19 Disease
Graft-Versus-Host Disease: Pathogenesis and Treatment
Involvement of the Purinergic System in Cell Death in Models of Retinopathies
Leukaemia: The Purinergic System and Small Extracellular Vesicles
Immunomodulatory Effects of a M2-Conditioned Medium (PRS CK STORM): Theory on the Possible Complex Mechanism of Action through Anti-Inflammatory Modulation of the TLR System and the Purinergic System
The Potential of the Purinergic System as a Therapeutic Target of Natural Compounds in Cutaneous Melanoma